Vertex Spring 2025 Co-op, Protein Sciences (San Diego, CA) ID-2095

November 29, 2024

Job Description

The Vertex Co-op Program offers students the opportunity to learn about the pharmaceutical industry from a hands-on perspective. You will be working closely with and learning from some of the brightest people in the industry. When you join our co-op program you should not be surprised to see that our environment is one that is innovative and team oriented, where collaboration is not just a word, and "we are relentless" is in everything we do. Students can expect to be challenged by their project plan, connect with other co-ops, and feel valued by the Vertex community. Not only will co-ops learn about their day-to-day tasks through their specific work assignments, but they will interact and have exposure to our organizational leaders and their teams.

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Job Summary:

Vertex Pharmaceuticals Inc. is seeking a highly motivated, creative and innovative co-op scientist to join our Protein Sciences San Diego team. As part of this program, the candidate will have the opportunity to work directly with a team of scientists responsible for applying integrative approaches to identify and characterize new biding sites / modes of action for therapeutics. The co-op will have an opportunity to propose and test new technologies to improve current workflows in order to facilitate CryoEM protein structure determination.

Key Responsibilities:

Project title: Develop and test new grid technologies to reduce protein needs for CryoEM studies

Under the supervision of a senior scientist at Vertex,

Express and purify proteins from recombinant and/or native sources
Propose and test new and emerging CryoEM grid technologies to improve internal structure determination workflows (lower protein needs and improved resolution). These efforts will support existing projects and facilitate the enablement of structural studies of low expressing, disease-relevant proteins from native sources.
Characterize the native environment of the protein using a relevant biochemical/biophysical assay (could include radiolabeled binding assays, kinetic assays, mass spectrometry, and/or fluorescent assays) to analyze protein quality suitable for CryoEM structural studies.

Qualifications:

Bachelor’s degree, and currently enrolled in a graduate degree program. Major in biology, biochemistry, chemistry, or chemical/biological/biochemical CryoEM experience is highly desirable but not required.
Basic knowledge of integral membrane protein purification techniques and biochemical/biophysical analysis methods.
Attention to detail, ability to accurately establish and follow protocols.
Strong communication and organization skills.
An open mindset and willingness to learn new techniques as needed to support the Protein Sciences group is desirable.
Permanent legal authorization to work in the United States
Candidate must be enrolled in an advanced degree program if graduating before June 2025

Vertex Spring 2025 Co-op, Protein Sciences (San Diego, CA) ID-2095

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...

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Other Jobs You May Be Interested In

Vertex Spring 2025 Co-op, Protein Sciences (San Diego, CA) ID-2095

Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

5. HOW DO YOU PROCESS INFORMATION?

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

8. HOW TO PRIORITIZE WORK?

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

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